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Sickle Cell Retinopathy

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Title: Sickle Cell Retinopathy

Author: Elizabeth Ann Urias, MSIV


Date: 06/24/2016

Image or video:

Keywords/Main Subjects: Sickle cell disease; sickle cell retinopathy; microvascular occlusion; retinal hemorrhage; salmon patch;

Diagnosis: Sickle Cell Retinopathy: Salmon Patch Hemorrhage

Description of Image: In sickle cell hemaglobinopathy, RBC sickling causes peripheral retinal arteriolar occlusion, leading to ischemic necrosis and weakening of the vessel walls. Fragile vessels result in hemorrhages in one or more layers of the retina. An intra-retinal hemorrhage is round or oval shaped, bright red, and measures ¼-1 disc diameter. In days or weeks, this bright red color becomes a salmon color, which is known as a “salmon patch.” After time, hemoglobin degradation occurs and the defect appears as bright yellow dots at several layers of the sensory retina, also known as “iridescent bodies.” (Bonanomi & Lavezzo, 2013)


Faculty Approval by: Griffin Jardine, MD

Identifier: Moran_CORE_21668

Financial Disclosures: None

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