Cryopyrin Associated Periodic Syndromes and the Eye
Title: Cryopyrin Associated Periodic Syndromes and the Eye
Author: Tom Oberg, MD
Keywords / Main Subjects: Cryopyrin associated periodic syndromes; Arthritis; Anakinra; NLRP3 gene; Uveitis; Non-pruritic urticaria; Auto-inflammatory disorders; Optic nerve edema; NOMID; IL-1;
Diagnosis: Cryopyrin associated periodic syndrome
Secondary CORE Categories: Pediatric Ophthalmology and Strabismus / Ocular Manifestations of Systemic Disease
Brief Description: This is a case report of a female child who presented with waxing and waning urticaria, anterior uveitis, arthritis, and papilledema. She had a previous diagnosis of cryopyrin associated periodic syndrome (Muckle-Wells syndrome). A discussion of cryopyrin associated periodic syndrome is undertaken including the diagnosis, clinical course, and treatment. A second patient is also reported.
Series: Moran Eye Center Grand Rounds 2012