Moran CORE

An e-channel resource

Open source ophthalmology education for students, residents, fellows, healthcare workers, and clinicians. Produced by the Moran Eye Center in partnership with the Eccles Library

Search Moran CORE

Intriguing Corneal Cases

Home / Refractive Surgery / Incisional Corneal Surgery

Title:  Intriguing Corneal Cases
Author:  Carlton Fenzl
Date:  10/29/2014
Keywords/Main Subjects: Corneal ring shaped opacity; MGUS; Corneal opacity; Irregular astigmatism; Penetrating keratoplasty; Post-keratoplasty; Astigmatic keratoplasty; LASIK after keratoplasty; Conductive keratoplasty; Compression sutures
Secondary CORE Category:  External Disease and Cornea / Systemic Disorders with Corneal Changes / Disorders of Immunoglobulin Synthesis
Additional CORE Category: External Disease and Cornea / Clinical Approach to Corneal Transplantation / Penetrating Keratoplasty
Diagnosis: MGUS, Irregular astigmatism
Brief Description: This is a series of 3 case studies of corneal disorders. The first covers an unknown diagnosis of a full thickness, ring-shaped corneal opacity. A differential of righ shaped opacities is discussed. The second case presents a patient with multiple white stromal opacities in the cornea. The diagnosis of MGUS is discussed. The third case covers a post-LASIK, post-cataract surgery patient who now presents with irregular astigmatism. A penetrating keratoplasty was performed with less than ideal results. The post-operative management of this penetrating keratoplasty is described. 
Format: video
Series: Moran Eye Center Grand Rounds
References:
Identifier: Moran_CORE_17700
Copyright statement: Copyright 2015. Please see terms of use page for more information.


Examining the Effects of Maternal Nutrition on Macular Development

Home / Principles of Ophthalmology / The Eye

Title:  Examining the Effects of Maternal Nutrition on Macular Development
Author:  Bradley Henricksen
Date:  09/17/2014
Keywords/Main Subjects: Macular development; Antioxidants; Vitamins; Carotenoids; Lutein; Zeaxanthin; Macular pigment optical density; MPOD
Secondary CORE Category:  Principles of Ophthalmology / Free Radicals and Antioxidants / Vulnerability of the Retina to Free Radicals
Diagnosis: None
Brief Description: This a report of the research study examining the relationship between maternal carotenoids and newborn pigment optical density and carotenoid status. Mother serum zeaxanthin levels correlated with infant zeaxanthin levels and macular pigment optical density.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_17688
Copyright statement: Copyright 2015. Please see terms of use page for more information.


A Brief Review of Oculocutaneous Albinism

Home / Ophthalmic Pathology and Intraocular Tumors / Retina and Retinal Pigment Epithelium

Title:  A Brief Review of Oculocutaneous Albinism (OA)
Author:  Christopher Ricks
Date:  09/17/2014
Keywords / Main Subjects: Chediak-Higashi; Albinism; Oculocutaneous albinism; Hermansk-Pudlak Syndrome; Foveal hypoplasia; Pendular nystagmus; Tyrosinase; Vici Syndrome
Secondary CORE Category: Retina and Vitreous / Retinal Degenerations Associated With Systemic Disease / Metabolic Diseases
Additional CORE Category: Pediatric Ophthalmology and Strabismus / Disorders of the Retina and Vitreous / Systemic Diseases and Disorders with Retinal Manifestations
Diagnosis: Oculocutaneous Albinism (OA)
Brief Description: This is a review of oculocutaneous albinism and all its forms. It also covers albinism syndroms such as Chediak-Higashi, Hermansky-Pudlak, and Vici Syndromes.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_17682
Copyright statement: Copyright 2015. Please see terms of use page for more information.


Back to Basics: Illumination Techniques

HomeExternal Disease and CorneaExamination Techniques for the External Eye and Cornea

Title: Back to Basics:  Illumination Techniques
Author:  Joshua Atkinson
Date:  09/17/2014
Keywords/Main Subjects: Illumination techniques; Slit lamp; Diffuse illumination; Direct focal illumination; Specular reflection; Retroillumination; Sclerotic scatter; Indirect lateral illumination
Secondary CORE Category: Optics / Optical Instruments and Low Vision Aids / Optical Instruments Used in Ophthalmic Practice
Diagnosis: None
Brief Description: This is a examination techniques presentation on methods of illumination used in the ophthalmic exam. It includes discussion of diffuse illumination, direct focal illumination, specular reflection, retroillumination, indirect lateral illumination, and sclerotic scatter.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_17672
Copyright statement: Copyright 2015. Please see terms of use page for more information.


Seeing is Believing in retinal Regeneration

Home / Principles of Ophthalmology / The Eye

Title:  Seeing is Believing in Retinal Regeneration
Author:  Rene Choi
Date:  10/15/2014
Secondary CORE Category:  Neuro-Ophthalmology/Evaluation of Diplopia/
Brief Description: 
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_17666
Copyright statement: Copyright 2015. Please see terms of use page for more information.


Use of Serum Biomarkers in NVAMD

HomeRetina and VitreousAge-Related Macular Degeneration and Other Causes of Choroidal Neovascularization

Title:  Use of Serum Biomarkers in Neovascular Age-Related Macular Degeneration (NVAMD)
Author:  Michael G. Taggart
Date:  08/20/2014
Keywords/Main Subjects: Age-related Macular Degeneration; AMD; Neovascular AMD;    Serum biomarkers; VEGF; Soluble FLT-1
Secondary CORE Category: Principles of Ophthalmology / Molecular Genetics
Diagnosis: Age-related Macular Degeneration (AMD)
Brief Description: This is a research presentation about the genetics and serum biomarkers for determining the risk of AMD. A review of neovascular AMD, risk genes, and environmental risk factors are discussed. The inflammatory serum biomarkers are discussed such as CRP. Levels of soluble FLT-1 level and their correlation with neovascular AMD is discussed.
Format: video
Series: Moran Eye Center Grand Rounds
References:
Identifier: Moran_CORE_17659
Copyright statement: Copyright 2015. Please see terms of use page for more information.


Innate Recognition of HSV-1: A View from Within The Cornea

HomeExternal Disease and Cornea / Infections Diseases of the External Eye: Basic Concepts and Viral Infections

Title:  Innate Recognition of HSV-1: A View from Within The Cornea
Author:  Christopher Conrady
Date:  10/08/2014
Keywords/Main Subjects: HSV-1; Herpes virus; Herpetic keratitis; Immunology; Innate imune system; Interferon; Toll-like receptor
Diagnosis: Herpetic keratitis
Brief Description: This is a research presentation of the role of the innate immune system in the recognition and response to herpes simplex virus 1. An extensive discussion of the molecular basis of HSV recognition and the specific molecules involved in corneal signalling is undertaken.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_17657
Copyright statement: Copyright 2015. Please see terms of use page for more information.


Stem/Progenitor Cells: Do they have a future in Retinal Vascular repair?

HomeRetina and VitreousRetinal Vascular Disease: Diabetic Retinopathy

Title: Stem cell progenitors – do they have a future in retinal vascular repair?
Author: Maria Grant
Date:  10/01/2014
Keywords/Main Subjects: Diabetic retinopathy; Stem cells; Angiogenesis; CD34 cells; Endothelial cells
Diagnosis: Diabetic retinopathy
Brief Description: This is a research presentation of the use of stem cells in treating and managing diabetic retinopathy. A review of the literature of diabetic retinopathy and stem cell use in medicine and specifically in the retina is presented. Using a mouse model, stem cell repair of oxygen induced retinopathy is investigated with new data presented. Mechanisms are discussed as well as techniques for acquiring and refining stem cells in humans.
Format: video
Series: Moran Eye Center Grand Rounds
References:
Identifier: Moran_CORE_17642
Copyright statement: Copyright 2015. Please see terms of use page for more information.


A New Animal Model for Senior-Loken Syndrome

HomeRetina and Vitreous / Hereditary and Choroidal Dystrophies

Title:  A New Animal Model for Senior-Loken Syndrome
Author:  Nikko Ronquilo
Date:  08/20/2014
Keywords/Main Subjects: Senior-Loken Syndrome; Medullary cystic kidney disease; Retinitis pigmentosa; Photoreceptor degeneration; Nyctalopia; NPHP5
Diagnosis: Senior-Loken Syndrome
Brief Description: This is a research presentation of the development of a mouse model of Senior-Loken syndrome. Using this model, the function of NPHP5, a gene commonly associated with Senior-Loken syndrome is investigated. In addition, a review of the pathogenesis, genetics, and clinical features of Senior-Loken syndrome in humans is presented.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_17644
Copyright statement: Copyright 2015. Please see terms of use page for more information.


Shallow Anterior Chamber in a Postoperative Patient

HomeGlaucoma / Surgical Therapy for Glaucoma

Title:  Shallow Anterior Chamber in a Postoperative Patient
Author:  Tara Tae, MSIV
Date:  08/13/2014
Keywords/Main Subjects: Ahmed valve; Glaucoma; Glaucoma surgery; Shallow anterior chamber; Trabeculectomy; Bleb; Choroidal detachment; Uveal effusion syndrome; Hypotony
Diagnosis: Choroidal detachment
Brief Description: This is a case presentation of a patient who presented with pain, vision loss, and shallow anterior chamber after glaucoma surgery using an Ahmed valve. A choroidal detachment was found secondary to hypotony. Hypotony and choroidal detachments are discusses as well as a review of other causes of choroidal detachment and its medical and surgical management. 
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_17634
Copyright statement: Copyright 2015. Please see terms of use page for more information.