Moran CORE

Open source ophthalmology education for students, residents, fellows, healthcare workers, and clinicians. Produced by the Moran Eye Center in partnership with the Eccles Library

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Senior-Loken Syndrome: From Human Genetics to an Animal Model

HomeRetina and Vitreous / Retinal Degenerations Associated with Systemic Disease

Title:  Senior-Loken Syndrome: From Human Genetics to an Animal Model
Author:  Nikko Ronquilo
Date:  02/13/2013
Keywords/Main Subjects: Senior-Loken Syndrome; Medullary cystic kidney disease; Retinitis pigmentosa; Photoreceptor degeneration; Nyctalopia; NPHP5
Secondary CORE Category:  Retina and Vitreous / Hereditary and Choroidal Dystrophies
Diagnosis: Senior-Loken Syndrome
Brief Description: This is a research presentation of the development of a mouse model of Senior-Loken syndrome. A review of the pathogenesis, genetics, and clinical features of Senior-Loken syndrome in humans is presented. Discussion of the primary cilium and its potential role in Senior-Loken syndrome is undertaken. The production and characterization of NPHP5 knockout mice is described.
Format: video
Series: Moran Eye Center Grand Rounds
References:
Identifier: Moran_CORE_15221
Copyright statement: Copyright 2015. Please see terms of use page for more information.


A Patient with Alternating Skew Deviation and Down-Beat Nystagmus

HomeNeuro-OphthalmologyNystagmus or Spontaneous Eye Movement Disorders

Title:  A Patient with Alternating Skew Deviation and Down-Beat Nystagmus
Author:  Kevin Meier
Date:  02/06/2013
Keywords/Main Subjects: Skew deviation; Downbeat nystagmus; Hypertropia; Alternating skew deviation
Secondary CORE Category:  Neuro-Ophthalmology / Evaluation of Diplopia / Supranuclear Causes of Diplopia
Diagnosis: Downbeat nystagmus, skew deviation
Brief Description: This is a case presentation of an elderly male with vertical binocular diplopia and downbeat nystagmus. It includes a discussion of the differential diagnoses for downbeat nystagmus and for skew deviation.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_15165
Copyright statement: Copyright 2015. Please see terms of use page for more information.


Orbitofacial Neurofibromatosis and Vision Loss

Home / Orbit, Eyelids, and Lacrimal System / Orbital Neoplasms and Malformations

Title: Orbitofacial Neurofibromatosis and Vision Loss
Author: Tyson Olson
Date: 2013
Keywords / Main Subjects: Neurofibromatosis type 1; Von Recklinghausen disease; Sphenoid wing dysplasia; Neurofibroma; Neurofibromin; S-shaped ptosis; Pulsatile proptosis; Orbitofacial neurofibromatosis; Lisch nodules;
Secondary CORE Category: Pediatric Ophthalmology and Strabismus / Ocular Manifestations of Systemic Disease / Diseases Due to Chromosomal Abnormalities
Diagnosis: Neurofibromatosis type 1
Brief Description: This is a case presentation of a male infant who presented with neurofibromatosis type 1. The presentation includes a discussion of the diagnostic criteria, clinical course, treatment, and prognosis of neurofibromatosis 1 (NF1). It also includes specific information about orbitofacial neurofibromatosis, a subset of NF1. The pathophysiology and molecular etiology of NF-1 are also discussed.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_15139
Copyright statement: Copyright 2015. Please see terms of use page for more information.


A Case Report of Recurrent Epithelial Irregularity

HomeExternal Disease and CorneaNeoplasms of the Conjunctiva and Cornea

Title:  A Case Report of Recurrent Epithelial Irregularity
Author:  Loren Imbornoni
Date:  07/17/2013
Keywords/Main Subjects: CIN; Epithelial irregularity; Corneal neoplasm; Conjunctiva neoplasm; Interferon; 5-fluorouracil
Diagnosis: CIN
Brief Description: This is a case presentation of a elderly male with several months of unilateral punctate epithelial infiltrates in a dendritic pattern and with pannus. The condition was unresponsive to antiviral, antibiotic, and anti-inflammatory treatment. A differential diagnosis is given. CIN is described in detail as well as the etiology and treatment of CIN.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_15109
Copyright statement: Copyright 2015. Please see terms of use page for more information.


Laser Astigmatic Correction: Using Intralase with Phacoemulsification

HomeLens and CataractSurgery for Cataract

Title:  Laser Astigmatic Correction: Using Intralase with Phacoemulsification
Author:  Max Padila
Date:  07/17/2013
Keywords/Main Subjects Cataract; Cataract Surgery; Intralase; Femtosecond laser; Assisted cataract surgery; Astigmatism; Limbal relaxing incision; Economics;
Diagnosis: Cataract; Astigmatism
Brief Description: This is a presentation of the use of femtosecond laser to correct astigmatism at the time of cataract surgery. Research data is presented of the results of femtosecond astigmatism correction. A discussion of the economics involved and relevant billing regulations in the USA is also presented.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_15095
Copyright statement: Copyright 2015. Please see terms of use page for more information.


18 Year-old Patient with Optic Neuropathy

HomeNeuro-OphthalmologyCauses of Decreased Vision

Title:  18 Year-old Patient with Optic Neuropathy
Author:  Derick Holt
Date:  06/19/2013
Keywords/Main Subjects: Neck stiffness; Optic nerve edema; Epstein-Barr virus; Optic neuritis
Diagnosis: EBV-induced Optic Neuritis
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_15075
Copyright statement: Copyright 2015. Please see terms of use page for more information.


OCT in the Assessment of Glaucoma

Home / Glaucoma / Clinical Evaluation

Title:  OCT in the Assessment of Glaucoma
Author:  Charles Weber
Date:  05/01/2013
Keywords/Main Subjects: OCT; RNFL; Glaucoma; Spectral domain OCT; Time domain OCT; OCT normative database; Retinal ganglion cell layer; Ganglion cell complex
Diagnosis: Glaucoma
Brief Description: This presentation covers the use of RNFL OCT in diagnosis and management of glaucoma. The specific types of OCT are discussed. Also discussed are the pitfalls of using OCT and how to avoid them. Important features of using the OCT are discussed and best practices in evaluating OCTs in managing glaucoma patients are discussed. Case studies are provided at the end.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_15063
Copyright statement: Copyright 2015. Please see terms of use page for more information.


What to Present, it is so Hard to Pick

HomeRetina and VitreousFocal and Diffuse Choroidal and Retinal Inflammation

Title:  What to Present, it is so Hard to Pick
Author:  Rob Hobbs
Date:  04/17/2013
Keywords/Main Subjects: PIC; Fluorescein angiogram; Punctate inner choroidopathy; White dot syndromes; MCP; Multifocal choroiditis
Diagnosis: Punctate inner choroidopathy
Brief Description: This is a case presentation of a patient with a white dot syndrome, punctate inner choroidopathy (PIC). An extensive discussion of the pathogenesis, clinical course, diagnosis of, and management of PIC. Current research in PIC is discussed. Treatment of PIC is discussed extensively. Fluorescein angiography and other diagnostic testing are also discussed extensively.
Format: video
Series: Moran Eye Center Grand Rounds
References:
Identifier: Moran_CORE_15058
Copyright statement: Copyright 2015. Please see terms of use page for more information.


A Patient with Fungal Keratitis

HomeExternal Disease and Cornea / Infections Diseases of the External Eye: Microbial and Parasitic Infections

Title:  A Patient with Fungal Keratitis
Author:  Adam Gess
Date:  03/20/2013
Keywords/Main Subjects: Fungal keratitis; Corneal transplant; Penetrating keratoplasty; Herpetic keratitis; Ulocladium
Diagnosis: Fungal keratitis
Brief Description: This is a case presentation of a patient with herpetic keratitis who had a penetrating keratoplasty followed by fungal keratitis in the graft. The clinical course and treatment of fungal keratitis in the setting of penetrating keratoplasty is discussed. A review of fungal keratitis is also presented
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_15050
Copyright statement: Copyright 2015. Please see terms of use page for more information.


A Complex Case of Aphakic Glaucoma

HomeGlaucomaChildhood Glaucoma

Title:  A Complex Case of Aphakic Glaucoma
Author:  James Tucker
Date:  03/13/2013
Keywords/Main Subjects: Aphakic glaucoma; Traumatic eye injury; Diurnal variation of intraocular pressure
Diagnosis: Aphakic glaucoma
Brief Description: This is a case presentation of an unusual teenage patient with aphakic glaucoma who presents with diurnal variations in visual acuity.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_15044
Copyright statement: Copyright 2015. Please see terms of use page for more information.