Moran CORE

An e-channel resource

Open source ophthalmology education for students, residents, fellows, healthcare workers, and clinicians. Produced by the Moran Eye Center in partnership with the Eccles Library

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Towards a Refined Understanding of the Genetics and Biology of Age-Related Macular Degeneration (AMD)

HomeRetina and VitreousAge-Related Macular Degeneration and other Causes of Choroidal Neovascularizaton

Title: Towards a Refined Understanding of the Genetics and Biology of Age-Related Macular Degeneration (AMD)
Author: Greg Hageman, MD
Date: 3/14/2012
Keywords/Main Subjects: Age-related macular degeneration
Diagnosis: Age-related Macular Degeneration (AMD)
Brief Description: This is a research presentation of the genetics and biology of age-related macular degeneration (ARMD, AMD). The discovery of the role of complement factor H and other complement pathways in AMD is discussed. ARMS2 and HTRA1 are also discussed. The presence of multiple phenotypes in AMD and their significance are discussed. Reticular pseudodrusen, drusen and other drusenoid materials are discussed. The systemic correlations between AMD and other disorders such as myocardial infarction are also discussed.
Format: video
Series: Moran Eye Center Grand Rounds
References:
Identifier: Moran_CORE_16651
Copyright statement: Copyright ©2015. Please see the Moran CORE terms of use for more information.


Simultaneous Bilateral Cataract Surgery

HomeLens and CataractSurgery for Cataract

Title: Simultaneous Bilateral Cataract Surgery
Author: Ambati, Crandall; Jacobson, Mamalis, Olson
Date: 05/02/2012
Keywords/Main Subjects: Cataract; Cataract Surgery; Ethics

Diagnosis: Cataract
Brief Description: This is a presentation of the pros and cons of doing bilateral sequential cataract surgery routinely in cataract surgery. A discussion of the best practices for bilateral sequential cataract surgery is undertaken. A review of the research is also undertaken.
Format: video
Identifier: Moran_CORE_16101
Series: Moran Eye Center Grand Rounds
Copyright statement: Copyright ©2015. Please see the Moran CORE terms of use for more information.


Bad Eyes, & Bad Ears Run in the Family

HomePediatric Ophthalmology and StrabismusOptic Disc Abnormalities

Title: Bad Eyes, & Bad Ears Run in the Family
Author: Leah Owen
Presentation Date: 05/23/2012
Keywords / Main Subjects: Optic atrophy; Autosomal dominant optic atrophy; Hearing loss; Kjer disease; OPA1 gene
Secondary CORE Categories: Neuro-OphthalmologyCauses of Decreased Vision / Optic Neuropathy
Diagnosis: Autosomal dominant (Kjer’s) Optic Atrophy
Brief Description: This is a case presentation of a child who presented with progressive worsening of vision and decreased hearing, with a family history of poor vision and hearing. The presentation discusses the differential diagnosis of optic atrophy in a child and discusses autosomal dominant (Kjer’s) optic atrophy in detail.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_16093
Copyright statement: Copyright ©2015. Please see the Moran CORE terms of use for more information.


Extracellular Signals Regarding Eye Development

HomePrinciples of OphthalmologyOcular Development

Title: Extracellular Signals Regarding Eye Development
Author: Sabine Fuhrmann
Date: 05/09/2012
Keywords/Main Subjects: Embryology of the eye; Developmental biology; RPE; Mitf; Beta-catenin; Focal dermal hypoplasia; Goltz syndrome; Porcupine; Coloboma; Pax2
Secondary CORE Categories: Principles of Ophthalmology /Ocular Development / Genetic Cascades and Morphogenic Gradients
Diagnosis: None
Brief Description: This presentation is a research report about the role of extracellular factors that regulate the embryological formation and development of the RPE. It concentrates on several proteins including porcupine, Pax2, laminin, and Mitf and their roles in development of the eye.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_16084
Copyright statement: Copyright ©2015. Please see the Moran CORE terms of use for more information.


Introduction to Genetic Counseling

HomePrinciples of OphthalmologyClinical Genetics

Title: Inroduction to Genetic Counseling
Author: Briana Sawyer
Date: 05/30/2012
Keywords/Main Subjects: Genetic counseling; Genetic testing
Diagnosis: None
Brief Description: This lecture provides and introduction to what genetic counseling involves in ophthalmology and an introduction to what the genetic counselor at the Moran Eye Center does for patients.
Format: video
Series: Moran Grand Rounds
Identifier: Moran_CORE_16068
Copyright statement: Copyright ©2015. Please see the Moran CORE terms of use for more information.


Floaters, Fatigue & Forgotten Insulin

HomeIntraocular Inflammation and Uveitis / Endophthalmitis

Title: Floaters, Fatigue & Forgotten Insulin
Author: Zachary Joos, MD
Date: 05/30/2012
Keywords/Main Subjects: Panuveitis; Subretinal abscess; Endophthalmitis; Hypopyon; Endogenous endophthalmitis
Secondary CORE Categories: General Medicine / Endocrine Disorders / Diabetes Mellitus
Diagnosis: Endogenous endophthalmitis
Brief Description: This is a case presentation of an older male with poorly controlled diabetes who presented with 3 days of dark floaters, decreased vision, and eye pain. On examination, this patient had anterior uveitis, keratic precipitates, and posterior uveitis. A discussion of the differential diagnosis for panuveitis in a poorly controlled diabetic is presented. This patient was diagnosed with endogenous endophthalmitis and a extensive discussion of the pathogenesis, organisms, clinical course, and treatment of endogenous endopthalmitis are presented.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_16052
Copyright statement: Copyright ©2015. Please see the Moran CORE terms of use for more information.


Optic Disc Edema with Macular Star or Neuroretinitis

HomeRetina and VitreousFocal and Diffuse Choroidal and Retinal Inflammation

Title: Optic Disc Edema with Macular Star or Neuroretinitis
Author: Krista Kinard
Date: 06/06/2012
Keywords/Main Subjects: Neuroretinitis; Macular star; Optic nerve edema; Optic nerve edema with macular star
Secondary CORE Categories: Intraocular Inflammation and Uveitis / Infectious Uveitis / Uveitis
Diagnosis: Neuroretinitis
Brief Description: This is a case study of a teenage female who presented with neck pain, neck stiffness, tinnitus, and blurry vision OU. On examination, dilated fundoscopic exam showed disc edema and macular star OU and mild vitreous cell. A discussion of the extensive differential diagnosis and methods of differentiating these items including appropriate laboratory testing are discussed. A discussion of the differences between neuroretinitis and optic disc edema with macular star is presented.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_16048
Copyright statement: Copyright ©2015. Please see the Moran CORE terms of use for more information.


Concurrent Open-Angle Glaucoma & Age-Related Macular Degeneration

HomeGlaucomaOpen Angle Glaucoma

Title:  Concurrent Open-Angle Glaucoma  & Age-Related Macular Degeneration
Author:  Jason Rupp, MSIV
Date:  07/20/2011
Keywords/Main Subjects: Glaucoma; Open angle glaucoma; AMD; Public health
Secondary CORE Category: RETINA AND VITREOUS / Age-Related Macular Degeneration and Other Causes of Choroidal Neovascularization / Age-Related Macular Degeneration
Diagnosis: Glaucoma and Macular degeneration
Brief Description: This presentation discusses the public health aspects of glaucoma and macular degeneration and the coprevalence of these two disorders. Community health initiatives and culturally relevant interventions are discussed.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_15985
Copyright statement: Copyright 2015. Please see terms of use page for more information.

 


Confocal Microscopy of the Cornea: Clinical Applications & Standardizing Data Acquisition

Home / External Disease and CorneaExamination Techniques for the External Eye and Cornea

Title: Confocal Microscopy of the Cornea Clinical Applications & Standardizing Data Acquisition
Author: Gene Kim MD
Date: 06/06/2012
Keywords/Main Subjects: Confocal microscopy; Fungal keratitis; Bacterial keratitis; Endothelial cell count; Acanthamoeba keratitis
Diagnosis: Keratitis
Brief Description: This is a presentation discussing the techniques and use of confocal microscopy in ophthalmology. Case presentations highlighting the benefits of confocal microscopy are given. A discussion of proper techniques, potential artifacts, and methods of standardizing data are given.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_15965
Copyright statement: Copyright ©2015. Please see the Moran CORE terms of use for more information.


A Big Blindspot

HomeNeuro-OphthalmologyCauses of Decreased Vision

Title: A Big Blindspot
Author: Brice Williams
Date: 06/13/2012
Keywords/Main Subjects: Big blindspot syndrome; Acute idiopathic blind spot enlargement syndrome; AIBSE
Diagnosis: Acute idiopathic blind spot enlargement syndrome
Brief Description: This is a case presentation of a middle-aged female who presented with unilateral dimness and a flashing grey spot in central vision. A differential diagnosis is discussed for unilateral enlarged blindspot and acute idiopathic blind spot enlargement syndrome is discussed in detail.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_15961
Copyright statement: Copyright ©2015. Please see the Moran CORE terms of use for more information.