Moran CORE

Open source ophthalmology education for students, residents, fellows, healthcare workers, and clinicians. Produced by the Moran Eye Center in partnership with the Eccles Library

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Ocular Manifestations of Fabry Disease

Home / Pediatric Ophthalmology and Strabismus / Ocular Manifestations of Systemic Disease

Title: Ocular Manifestations of Fabry Disease
Author: Ethan Tittler
Date: 2010
Keywords / Main Subjects: Fabry Disease; Disorders of lipid metabolism; Cloudy cornea; Renal failure; Peripheral neuropathy; Lysosomal inclusions; Alpha-galactosidase; A X-linked recessive; Corneal verticillata; Enlarged corneal nerves
Secondary CORE Category: External Disease and Cornea / Systemic Disorders with Corneal Changes / Disorders of Lipid Metabolism and Storage
Third CORE Category: Retina and Vitreous / Retinal Degenerations Associated with Systemic Disease / Metabolic Diseases
Diagnosis: Fabry Disease
Brief Description: This is a review and hypothetical case report covering the diagnosis, pathogenesis, clinical course, and prognosis of Fabry disease. The genetics and electron microscopic histopathology are also covered in this presentation. Attention is paid to systemic signs and ocular signs.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_14826
Copyright statement: Copyright 2015. Please see terms of use page for more information.


Modulation of Soluble FLT-1: Ocular Implications and Beyond

Home / External Disease and Cornea / Ocular Immunology

Title:  Modulation of Soluble FLT-1: Ocular Implications and Beyond
Author:  Leah Owen
Date:  09/08/2010
Keywords/Main Subjects: Angiogenesis; VEGF; Soluble FLT-1; Morpholinos
Diagnosis: Corneal neovascularization
Brief Description: This is a research presentation discussing soluble FLT-1 and its role in the maintainence of avascular corneal tissue. The use of morpholinos in modifying expression of soluble FLT-1 is presented. 
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_14822
Copyright statement: Copyright 2015. Please see terms of use page for more information.


Multifocal Intraocular Lens Exchange: Case Studies

Home / Lens and Cataract / Surgery for Cataracts

Title:  Multifocal Intraocular Lens Exchange: Case Studies
Author:  Shaheen Kavoussi
Date:  2010
Keywords/Main Subjects: Multifocal IOL; IOL exchange; Dysphotopsia; ReStor; ReZoom; Presbyopia; Patient expectations
Secondary CORE Category:  Clinical Optics / Intraocular Lenses / Multifocal Intraocular Lenses
Third Core Category: Refractive Surgery / Accomodative and Nonaccomodative Treatment of Presbyopia
Diagnosis: Multifocal IOL exchange
Brief Description: This is a clinical research presentation reviewing the types of multifocal lenses and the complications and indications for intraocular lens (IOL) exchange with multifocal IOLS. This study presents the demographics of patients who had originally had multifocal IOLs and had subsequent IOL removal. Surgical photos of IOL removal is shown. A discussion of multiple patient types is shown for who would and would not be a good candidate for multifocal IOLs.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_14815
Copyright statement: Copyright 2015. Please see terms of use page for more information.


Introducing a New Member of the VEGF Family

Home / External Disease and Cornea / Ocular Immunology

Title:  Introducing a New Member of the VEGF Family
Author:  Romulo Albuquerque
Date:  10/20/2010
Keywords/Main Subjects: Angiogenesis; VEGF; Hemangiogenesis; Lymphangiogenesis; Soluble VEGF receptor 2
Diagnosis: Lymphangiogenesis
Brief Description: 
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_14799
Copyright statement: Copyright 2015. Please see terms of use page for more information.


4 Year-Old with Anterior Chamber Mass

Home / Pediatric Ophthalmology and Strabismus / Disorders of the Retina and Vitreous

Title: 4 Year-Old with Anterior Chamber Mass
Author: Lloyd Williams
Date: 2010
Keywords / Main Subjects: Medulloepithelioma; Persistent fetal vasculature; Spontaneous hyphema; Anterior chamber mass; Ocular ultrasound; Microphthalmos;
Secondary CORE Categories: Lens and Cataract / Embryology and Developmental Defects of the Lens / Developmental Defects
Diagnosis: None
Brief Description: This is a case report of a young male child who presented with an anterior chamber mass and spontaneous hyphema. A differential diagnosis of the mass is given and some discussion of each aspect of the differential is given. The final diagnosis is unknown.
Format: video
Series: Moran Eye Center Grand Rounds 2010
Identifier: Moran_CORE_14794
Copyright statement: Copyright 2015. Please see terms of use page for more information.


Pediatric Patient with and Anterior Segment Mass: A Case Presentation

Home / Pediatric Ophthalmology and Strabismus / Disorders of the Retina and Vitereous

Title: Pediatric Patient with and Anterior Segment Mass: A Case Presentation
Author: David Gay
Date: 10/20/2010
Keywords / Main Subjects: Medulloepithelioma; Persistent fetal vasculature; Spontaneous hyphema; Anterior chamber mass; Ocular ultrasound; Microphthalmos
Secondary CORE Category: Lens and Cataract/Embryology and Developmental Defects of the Lens/Developmental Defects
Diagnosis: None
Brief Description: This is a case report of a young male child who presented with an anterior chamber mass and spontaneous hyphema. A differential diagnosis of the mass is given and some discussion of each aspect of the differential is given. The final diagnosis is unknown.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_14787
Copyright statement: Copyright 2015. Please see terms of use page for more information.


CMV Retinitis

Home / Intraocular Inflammation and Uveitis / Ocular Involvement in AIDS (HIV)

 

Title:  CMV Retinitis
Author:  Stewart Walther
Date:  10/20/2010
Keywords/Main Subjects: HIV; AIDS; Cytomegalovirus; CMV retinitis; Valganciclovir; Intravitreal antiviral therapy
Secondary CORE Category:  Retina and Vitreous / Focal and Diffuse Choroidal and Retinal Inflammation / Infectious Retinal and Choroidal Inflammation
Diagnosis: CMV retinitis
Brief Description: This is a case presentation of a middle-aged male who is immunocompromised due to HIV/AIDS who presented with altered mental status and altered visual acuity in the right eye. He was diagnosed with CMV retinitis. A discussion of the CMV virus, its clinical course in the retina, etiology, and management of CMV retinitis is presented. Stagin of CMV retinitis is also discussed. 
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_14777
Copyright statement: Copyright 2015. Please see terms of use page for more information.


An Update on Current Concepts and Controversies in Idiopathic Intracranial Hypertension

Home / Neuro-ophthalmology / Decreased Vision

Title: An Update on Current Concepts and Controversies in Idiopathic Intracranial Hypertension (IIH)
Author: Kathleen Digre
Date: 11/17/2010
Keywords / Main Subjects: Pseudotumor; IIH; Optic nerve edema; Obesity; Idiopathic intracranial hypertension; MRI; Lumbar puncture
Secondary CORE Category: Pediatric Ophthalmology and Strabismus / Optic Disc Abnormalities / Idiopathic Intracranial Hypertension
Diagnosis: Idiopathic Intracranial Hypertension
Brief Description: This is a clinical review of idiopathic intracranial hypertension (IIH), also known as pseudotumor cerebri. It also discusses the current controversies in the nomenclature, imaging, pathophysiology and treatment of IIH as well as discussing the role of obesity and papilledema in IIH.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_14720
Copyright statement: Copyright 2015. Please see terms of use page for more information.


Cornea Mystery

Home / External Disease and Corena / Clinical Approach to Ocular Surface Disorders

Title:  Cornea Mystery
Author:  Shameema Sikder
Date: 12/01/2010
Keywords/Main Subjects: Corneal epitheliopathy; Post-LASIK complications
Diagnosis: None
Brief Description: This is a case report of a man who post-cataract surgery had a poor refractive outcome and had a secondary treatment with LASIK, also with a poor refractive outcome. Some corneal epitheliopathy was seen on exam, but a final diagnosis was not able to be made at the time of the presentation. 
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_14705
Copyright statement: Copyright 2015. Please see terms of use page for more information.


Glaucoma: A Vascular Mediated Pathology

Home / Glaucoma / Open Angle Glaucoma

 

Title:  Glaucoma: A Vascular Mediated Pathology
Author:  Barbara Wirostko
Date:  12/08/2010
Keywords/Main Subjects: Glaucoma; Ocular perfusion pressure; Glaucoma treatments;  IOP variation; Drug development; Endothelial cells; Vascular autoregulation; Nitric oxide; VEGF; Endothelin
Diagnosis: Glaucoma
Brief Description: This presentation provides an extensive review of the effects of vascular perfusion and intraocular pressure in glaucoma and normal tension glaucoma. A discussion of how to measure the vascular perfusion of the eye is undertaken. Drug development with regard to vascular perfusion of the eye and glaucoma is discussed.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_14685
Copyright statement: Copyright 2015. Please see terms of use page for more information.