Lessons from the Largest Case-Control Study of Age-related Macular Degeneration
Title: Lessons from the Largest Case-Control Study of Age-related Macular Degeneration
Author: Lars Fritsche
Keywords/Main Subjects: ARMD, Genetics, Complement factor H, HTRA-1
Secondary CORE Category: Principles of Ophthalmology / Clinical Genetics/ Complex genetic disease: polygenic and multifactorial inheritance
Diagnosis: Age-related Macular Degeneration
Brief Description: This is a basic research presentation of research on the genetics of ARMD. The known genetics of ARMD is discussed first followed by a discussion of the International AMD Genetics Consortium work. Design of experiments and single variant and gene-based test results are discussed. A summary of current work and potential future work is undertaken as well.
Series: Moran Eye Center Grand Rounds