Moran CORE

An e-channel resource

Open source ophthalmology education for students, residents, fellows, healthcare workers, and clinicians. Produced by the Moran Eye Center in partnership with the Eccles Library

Search Moran CORE

Integrated Analysis of Gene Expression, Genetics and Epigenetics

HomeRetina and VitreousAge-Related Macular Degeneration and other Causes of Choroidal Neovascularization

Title: Integrated Analysis of Gene Expression, Genetics and Epigenetics Suggests a Role for Lipid Metabolilsm in Involved in Age-Related Macular Deneneration
Author: Margaret DeAngelis, M.D., Ph.D, Associate Professor of Ophthalmology and Visual Sciences
Date: 01/04/2014
Keywords/Main Subjects: Polygenic; Multifactorial Inheritance; Genetic disease; Genome; ARMD; Whole exome sequencing; Epigentics; ABCA1
Secondary CORE Category: Principles of Ophthalmology/ Clinical Genetics / Complex Genetic Disease: Polygenic and Multifactorial Inheritance
Diagnosis: None
Brief Description: This is a research presentation on the use of SNPs and genomics to determine genes associated with ARMD. In particular, ABCA1, a cholesterol efflux pum protein in the statin pathway, is discussed as a gene important in ARMD risk.
Format: video
Series: Moran Eye Center Grand Rounds
Identifier: Moran_CORE_15406
Copyright statement: Copyright 2015. Please see terms of use page for more information.